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PMP70 Rabbit pAb

Cat No.: APA1790
Size:
Product Name: PMP70 Rabbit pAb
Cat No.: APA1790
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:50
FC: 1:20-1:100
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human PMP70
calculated molecular weight: 76 kDa
observed molecular weight: 70 kDa
genbank accession number: P28288
gene id (ncbi): 5825
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ZWS2; ABC43; CBAS5; PMP70; PXMP1
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]