MMP7 Rabbit pAb
Cat No.: APA1781
Size：
| Product Name: | MMP7 Rabbit pAb |
| Cat No.: | APA1781 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:200 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human MMP7 |
| calculated molecular weight: | 30 kDa |
| observed molecular weight: | 30 kDa |
| genbank accession number: | P09237 |
| gene id (ncbi): | 4316 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | MMP-7; MPSL1; PUMP-1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016] |