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Caspase-2 Rabbit pAb

Cat No.: APA1778
Size:
Product Name: Caspase-2 Rabbit pAb
Cat No.: APA1778
source: Rabbit
reactivity: Human
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Caspase-2
calculated molecular weight: 51 kDa
observed molecular weight: 51 kDa
genbank accession number: P42575
gene id (ncbi): 835
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer--s disease, Huntington--s disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]