Argininosuccinate Lyase Rabbit pAb
Cat No.: APA1735
Size:
Product Name: | Argininosuccinate Lyase Rabbit pAb |
Cat No.: | APA1735 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human Argininosuccinate Lyase |
calculated molecular weight: | 52 kDa |
observed molecular weight: | 52 kDa |
genbank accession number: | P04424 |
gene id (ncbi): | 435 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | ASAL |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |