TAB3 Rabbit pAb
Cat No.: APA1719
Size：
| Product Name: | TAB3 Rabbit pAb |
| Cat No.: | APA1719 |
| source: | Rabbit |
| reactivity: | Human, Mouse |
| applications: | WB,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 ICC/IF: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human TAB3 |
| calculated molecular weight: | 79 kDa |
| observed molecular weight: | 82 kDa |
| genbank accession number: | Q8N5C8 |
| gene id (ncbi): | 257397 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | NAP1; MAP3K7IP3 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |