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Fibromodulin Rabbit pAb

Cat No.: APA1699
Size:
Product Name: Fibromodulin Rabbit pAb
Cat No.: APA1699
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Fibromodulin
calculated molecular weight: 43 kDa
observed molecular weight: 60 kDa
genbank accession number: Q06828
gene id (ncbi): 2331
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: FM; SLRR2E
category: Primary Ab
concentration: 0.5mg/ml
background: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]