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MMP20 Rabbit pAb

Cat No.: APA1694
Size:
Product Name: MMP20 Rabbit pAb
Cat No.: APA1694
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human MMP20
calculated molecular weight: 54 kDa
observed molecular weight: 54 kDa
genbank accession number: O60882
gene id (ncbi): 9313
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AI2A2; MMP-20
category: Primary Ab
concentration: 0.5mg/ml
background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP--s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3. [provided by RefSeq, Aug 2011]