GAB2 Rabbit pAb
Cat No.: APA1684
Size：
| Product Name: | GAB2 Rabbit pAb |
| Cat No.: | APA1684 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 ICC/IF: 1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human GAB2 |
| calculated molecular weight: | 75 kDa |
| observed molecular weight: | 98 kDa |
| genbank accession number: | Q9UQC2 |
| gene id (ncbi): | 9846 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | KIAA0571; GRB2-associated-binding protein 2; GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009] |