TL1A Rabbit pAb
Cat No.: APA1637
Size：
| Product Name: | TL1A Rabbit pAb |
| Cat No.: | APA1637 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human TL1A |
| calculated molecular weight: | 28 kDa |
| observed molecular weight: | 28 kDa |
| genbank accession number: | O95150 |
| gene id (ncbi): | 9966 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | TL1; TL1A; VEGI; TNLG1B; VEGI192A |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] |