JNK3 Rabbit pAb
Cat No.: APA1611
Size:
Product Name: | JNK3 Rabbit pAb |
Cat No.: | APA1611 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:200-1:1000 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human JNK3 |
calculated molecular weight: | 53 kDa |
observed molecular weight: | 53 kDa |
genbank accession number: | P53779 |
gene id (ncbi): | 5602 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017] |