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JNK3 Rabbit pAb

Cat No.: APA1611
Size:
Product Name: JNK3 Rabbit pAb
Cat No.: APA1611
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:50
FC: 1:200-1:1000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human JNK3
calculated molecular weight: 53 kDa
observed molecular weight: 53 kDa
genbank accession number: P53779
gene id (ncbi): 5602
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]