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PD1 Rabbit pAb

Cat No.: APA1608
Size:
Product Name: PD1 Rabbit pAb
Cat No.: APA1608
source: Rabbit
reactivity: Human
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human PD1
calculated molecular weight: 32 kDa
observed molecular weight: 52-65 kDa
genbank accession number: Q15116
gene id (ncbi): 5133
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]