IL3RA/CD123 Rabbit pAb
Cat No.: APA1596
Size:
Product Name: | IL3RA/CD123 Rabbit pAb |
Cat No.: | APA1596 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human IL3RA/CD123 |
calculated molecular weight: | 43 kDa |
observed molecular weight: | 70 kDa |
genbank accession number: | P26951 |
gene id (ncbi): | 3563 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012] |