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Syntaxin 1a Rabbit pAb

Cat No.: APA1570
Size:
Product Name: Syntaxin 1a Rabbit pAb
Cat No.: APA1570
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Syntaxin 1a
calculated molecular weight: 33 kDa
observed molecular weight: 33 kDa
genbank accession number: Q16623
gene id (ncbi): 6804
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: STX1; HPC-1; P35-1; SYN1A
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]