Syntaxin 1a Rabbit pAb
Cat No.: APA1570
Size:
Product Name: | Syntaxin 1a Rabbit pAb |
Cat No.: | APA1570 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000-1:10000 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Syntaxin 1a |
calculated molecular weight: | 33 kDa |
observed molecular weight: | 33 kDa |
genbank accession number: | Q16623 |
gene id (ncbi): | 6804 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | STX1; HPC-1; P35-1; SYN1A |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |