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Collagen II Rabbit pAb

Cat No.: APA1550
Size:
Product Name: Collagen II Rabbit pAb
Cat No.: APA1550
source: Rabbit
reactivity: Human, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Collagen II
calculated molecular weight: 142 kDa
observed molecular weight: 30 kDa (Isoform 3) kDa
genbank accession number: P02458
gene id (ncbi): 1280
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AOM; ANFH; SEDC; STL1; COL11A3
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]