Desmoglein 1/DSG1 Rabbit pAb
Cat No.: APA1542
Size：
| Product Name: | Desmoglein 1/DSG1 Rabbit pAb |
| Cat No.: | APA1542 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human Desmoglein 1/DSG1 |
| calculated molecular weight: | 114 kDa |
| observed molecular weight: | 114 kDa |
| genbank accession number: | Q02413 |
| gene id (ncbi): | 1828 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | DG1; DSG; CDHF4; EPKHE; PPKS1; SPPK1; EPKHIA |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015] |