ENPP1 Rabbit pAb
Cat No.: APA1528
Size:
Product Name: | ENPP1 Rabbit pAb |
Cat No.: | APA1528 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human ENPP1 |
calculated molecular weight: | 105 kDa |
observed molecular weight: | 140 kDa |
genbank accession number: | P22413 |
gene id (ncbi): | 5167 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | M6S1; NPP1; NPPS; PC-1; PCA1; ARHR2; COLED; PDNP1 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5-- triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with --idiopathic-- infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008] |