ENPP1 Rabbit pAb
Cat No.: APA1527
| Product Name: | ENPP1 Rabbit pAb |
| Cat No.: | APA1527 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human ENPP1 |
| calculated molecular weight: | 105 kDa |
| observed molecular weight: | 140 kDa |
| genbank accession number: | P22413 |
| gene id (ncbi): | 5167 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | M6S1; NPP1; NPPS; PC-1; PCA1; ARHR2; COLED; PDNP1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5-- triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with --idiopathic-- infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008] |
