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ENPP1 Rabbit pAb

Cat No.: APA1527
Size:
Product Name: ENPP1 Rabbit pAb
Cat No.: APA1527
source: Rabbit
reactivity: Human
applications: WB,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human ENPP1
calculated molecular weight: 105 kDa
observed molecular weight: 140 kDa
genbank accession number: P22413
gene id (ncbi): 5167
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: M6S1; NPP1; NPPS; PC-1; PCA1; ARHR2; COLED; PDNP1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5-- triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with --idiopathic-- infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008]