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IL-6 Rabbit pAb

Cat No.: APA1475
Size:
Product Name: IL-6 Rabbit pAb
Cat No.: APA1475
source: Rabbit
reactivity: Human
applications: WB,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:20
FC: 1:50
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human IL-6
calculated molecular weight: 24 kDa
observed molecular weight: 21-28 kDa
genbank accession number: P05231
gene id (ncbi): 3569
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]