Granzyme B Rabbit pAb
Cat No.: APA1472
Size：
| Product Name: | Granzyme B Rabbit pAb |
| Cat No.: | APA1472 |
| source: | Rabbit |
| reactivity: | Mouse |
| applications: | WB,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 FC: 1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse Granzyme B |
| calculated molecular weight: | 28 kDa |
| observed molecular weight: | 28 kDa |
| genbank accession number: | P04187 |
| gene id (ncbi): | 14939 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | GZB; CCP1; Ctla1; Ctla-1; AI553453; CCP-1/C11 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis. [provided by RefSeq, Sep 2016] |