CD177 Rabbit pAb
Cat No.: APA1462
Size:
Product Name: | CD177 Rabbit pAb |
Cat No.: | APA1462 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:200 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human CD177 |
calculated molecular weight: | 46 kDa |
observed molecular weight: | 70 kDa |
genbank accession number: | Q8N6Q3 |
gene id (ncbi): | 57126 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener--s granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014] |