CD177 Rabbit pAb
Cat No.: APA1462
Size：
| Product Name: | CD177 Rabbit pAb |
| Cat No.: | APA1462 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:200 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human CD177 |
| calculated molecular weight: | 46 kDa |
| observed molecular weight: | 70 kDa |
| genbank accession number: | Q8N6Q3 |
| gene id (ncbi): | 57126 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener--s granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014] |