IL-6R Rabbit pAb
Cat No.: APA1457
Size：
| Product Name: | IL-6R Rabbit pAb |
| Cat No.: | APA1457 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human IL-6R |
| calculated molecular weight: | 52 kDa |
| observed molecular weight: | 40-80 kDa |
| genbank accession number: | P08887 |
| gene id (ncbi): | 3570 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011] |