ABCB11/BSEP Rabbit pAb
Cat No.: APA1447
Size：
| Product Name: | ABCB11/BSEP Rabbit pAb |
| Cat No.: | APA1447 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | IHC,ICC/IF,FC |
| clonality: | Polyclonal |
| recommended dilution: | IHC: 1:50 ICC/IF: 1:50 FC: 1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human ABCB11/BSEP |
| calculated molecular weight: | 146 kDa |
| observed molecular weight: | |
| genbank accession number: | O95342 |
| gene id (ncbi): | 8647 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008] |