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TLR8 Rabbit pAb

Cat No.: APA1442
Size:
Product Name: TLR8 Rabbit pAb
Cat No.: APA1442
source: Rabbit
reactivity: Human
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human TLR8
calculated molecular weight: 120 kDa
observed molecular weight: 150 kDa
genbank accession number: Q9NR97
gene id (ncbi): 51311
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CD288
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008]