FADD Rabbit pAb
Cat No.: APA1411
Size：
| Product Name: | FADD Rabbit pAb |
| Cat No.: | APA1411 |
| source: | Rabbit |
| reactivity: | Mouse |
| applications: | WB,IHC,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:50 FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of mouse FADD |
| calculated molecular weight: | 23 kDa |
| observed molecular weight: | 28 kDa |
| genbank accession number: | Q61160 |
| gene id (ncbi): | 14082 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Mort1/FADD |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). |