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Angiopoietin 1 Rabbit pAb

Cat No.: APA1400
Size:
Product Name: Angiopoietin 1 Rabbit pAb
Cat No.: APA1400
source: Rabbit
reactivity: Human, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Angiopoietin 1
calculated molecular weight: 58 kDa
observed molecular weight: 75 kDa
genbank accession number: Q15389
gene id (ncbi): 284
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AGP1; AGPT; ANG1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]