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Integrin beta 4 Rabbit pAb

Cat No.: APA1389
Size:
Product Name: Integrin beta 4 Rabbit pAb
Cat No.: APA1389
source: Rabbit
reactivity: Human, Mouse
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
format: Liquid
isotype: IgG
immunogen: Recombinant protein of mouse Integrin beta 4
calculated molecular weight: 202 kDa
observed molecular weight: 202 kDa
genbank accession number: A2A863
gene id (ncbi): 192897
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CD104; AA407042; C230078O20
category: Primary Ab
concentration: 0.5mg/ml
background: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]