Integrin beta 4 Rabbit pAb
Cat No.: APA1389
Size:
Product Name: | Integrin beta 4 Rabbit pAb |
Cat No.: | APA1389 |
source: | Rabbit |
reactivity: | Human, Mouse |
applications: | WB,IHC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse Integrin beta 4 |
calculated molecular weight: | 202 kDa |
observed molecular weight: | 202 kDa |
genbank accession number: | A2A863 |
gene id (ncbi): | 192897 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CD104; AA407042; C230078O20 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |