Survivin Rabbit pAb
Cat No.: APA1370
Size:
Product Name: | Survivin Rabbit pAb |
Cat No.: | APA1370 |
source: | Rabbit |
reactivity: | Mouse, Rat |
applications: | WB,IHC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:20-1:500 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse Survivin |
calculated molecular weight: | 16 kDa |
observed molecular weight: | 16 kDa |
genbank accession number: | O70201 |
gene id (ncbi): | 11799 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | Api4; TIAP; AAC-11; survivin40 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. In humans, gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts have been identified in human that regulate this gene--s expression. At least three transcript variants encoding distinct isoforms have been found for this gene, although at least one of these transcript variants is a nonsense-mediated decay (NMD) candidate. [provided by RefSeq, Jul 2008] |