Fluor® 647 Anti-Human CD20 Antibody[2H7]
Cat No.: FCE3476
Size:
Product Name: | Fluor® 647 Anti-Human CD20 Antibody[2H7] |
Cat No.: | FCE3476 |
host: | Mouse |
uniprot id: | P11836 |
geneid: | 931 |
application: | FCM |
isotype: | Mouse IgG2b, κ |
form: | Liquid |
storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
shipping: | Ice bag |
category id: | Flow Cytometry Antibodies |
abbreviation: | CD20 |
conjugation: | Fluor® 647 |
species reactivity: | Human |
usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
clone no.: | 2H7 |
background: | CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82. |
target synonym: | Bp35;Leukocyte surface antigen Leu-16;MS4A1;B-lymphocyte surface antigen B1; |
concentration: | 5 μL/Test |
buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
image 1 description: | Human peripheral blood lymphocytes are stained with Fluor® 647 Anti-Human CD20 Antibody (filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control. |