Purified Anti-Human CD20 Antibody[2H7]
Cat No.: FCE3467
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| Product Name: | Purified Anti-Human CD20 Antibody[2H7] |
| Cat No.: | FCE3467 |
| host: | Mouse |
| uniprot id: | P11836 |
| geneid: | 931 |
| application: | FCM |
| isotype: | Mouse IgG2b, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD20 |
| conjugation: | Unconjugated |
| species reactivity: | Human |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| clone no.: | 2H7 |
| background: | CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82. |
| target synonym: | Bp35;Leukocyte surface antigen Leu-16;MS4A1;B-lymphocyte surface antigen B1; |
| concentration: | 0.5 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
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