Biotin Anti-Human CD123 Antibody[6H6]
Cat No.: FCE2625
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Product Name: | Biotin Anti-Human CD123 Antibody[6H6] |
Cat No.: | FCE2625 |
host: | Mouse |
uniprot id: | P26951 |
geneid: | 3563 |
application: | FCM |
isotype: | Mouse IgG1, κ |
form: | Liquid |
storage: | This product can be stored at 2-8°C for 12 months. Do not freeze. |
shipping: | Ice bag |
category id: | Flow Cytometry Antibodies |
abbreviation: | CD123 |
conjugation: | Biotin |
species reactivity: | Human |
usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
clone no.: | 6H6 |
background: | CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells. |
target synonym: | IL-3Rα; IL-3 Receptor alpha; |
concentration: | 0.5 mg/mL |
buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
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