AF/LE Purified Anti-Human CD8a Antibody[OKT-8]
Cat No.: FCE2504
Size：
| Product Name: | AF/LE Purified Anti-Human CD8a Antibody[OKT-8] |
| Cat No.: | FCE2504 |
| host: | Mouse |
| uniprot id: | P01732 |
| geneid: | 925 |
| application: | FCM,Depletion |
| isotype: | Mouse IgG2a, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD8 |
| conjugation: | None (Purified antibody-Azide Free/Low endotoxin) |
| species reactivity: | Human |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| clone no.: | OKT-8 |
| background: | CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck. |
| target synonym: | T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL; |
| concentration: | 0.5 mg/mL |
| buffer: | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| image 1 description: | |
| @@: |